Guyton and Hall Textbook of Medical Physiology 14th Edition 2021

 

Book Metadata

• Full Title: Guyton and Hall Textbook of Medical Physiology, 14th Edition

• Editors and Authors:

1. Authors: John E. Hall, PhD and Michael E. Hall, MD, MS

2. Legacy Author: Arthur C. Guyton, MD (Author of the first eight editions)

• Year of Publication: 2021

• Total Number of Pages: 1028 pages.

Copyright Summary

This textbook is published by Elsevier, Inc. and is the fourteenth edition of a work originally copyrighted in 1956. It is protected under international copyright law with the standard ISBN: 978-0-323-59712-8 (International Edition ISBN: 978-0-323-67280-1). 

The copyright notice includes a legal disclaimer advising practitioners to rely on their own clinical experience and verify diagnoses and drug dosages independently due to rapid advances in medical science.

Preface Analysis

The authors’ primary intent is to explain complex physiological principles in language that is easily understood by students, continuing a 65-year tradition established by Dr. Arthur Guyton. 

The book aims to fill the clinical gap between basic science and the pathophysiology of human disease, focusing on how the body's cells, tissues, and organs integrate into a functional whole through homeostasis.

While the primary audience includes medical, dental, and nursing students, the authors explicitly state the text is intended for physicians and healthcare professionals who require a comprehensive review of the basic principles necessary for clinical practice. 

To enhance utility, the text utilizes two print sizes: large print for fundamental information and small print for specialized clinical information or in-depth physiological mechanisms.

Chapter List

• Chapter 1: Functional Organization of the Human Body and Control of the “Internal Environment”

• Chapter 2: The Cell and Its Functions

• Chapter 3: Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction

• Chapter 5: Membrane Potentials and Action Potentials

• Chapter 12: Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial Analysis

• Chapter 15: Vascular Distensibility and Functions of the Arterial and Venous Systems

• Chapter 20: Cardiac Output, Venous Return, and Their Regulation

• Chapter 21: Muscle Blood Flow and Cardiac Output During Exercise: the Coronary Circulation and Ischemic Heart Disease

• Chapter 26: Urine Formation by the Kidneys: I. Glomerular Filtration, Renal Blood Flow, and Their Control

• Chapter 39: Pulmonary Circulation, Pulmonary Edema, and Pleural Fluid

• Chapter 40: Principles of Gas Exchange; Diffusion of Oxygen and Carbon Dioxide Through the Respiratory Membrane

• Chapter 41: Transport of Oxygen and Carbon Dioxide in Blood and Tissue Fluids

• Chapter 45: Physiology of Deep-Sea Diving and Other Hyperbaric Conditions

• Chapter 71: The Liver

• Chapter 72: Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals

• Chapter 76: Pituitary Hormones and Their Control by the Hypothalamus

• Chapter 80: Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth

• Chapter 83: Pregnancy and Lactation

Clinical Value Prop: Why Read This?

For the practicing physician, this text serves as a vital bridge between theoretical biology and clinical medicine. It provides the physiological foundation for understanding how homeostatic compensations—which may initially maintain life—can eventually lead to long-term organ damage, such as the relationship between renal salt excretion and chronic hypertension.

The inclusion of pathophysiology throughout the text ensures that the reader understands the "why" behind disordered body functions. Furthermore, the specialized small-print sections provide high-yield clinical insights tailored to specific medical fields, making it a functional reference for both generalists and specialists. 

Professionals will find the integrated systems approach invaluable for diagnosing complex multi-organ conditions where individual parts cannot be viewed in isolation.

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