2025 CURRENT Medical Diagnosis & Treatment (CMDT)

The front cover of '2025 CURRENT Medical Diagnosis & Treatment' features a blue background with the title in large white and light blue letters. The year '2025' is displayed centrally in a large, white font above a red banner that reads 'UPDATED ANNUALLY'. To the left of the center, there are two small inset images: the top one shows a female physician in a white coat speaking to a patient, and the bottom one is a blue medical illustration of a human torso highlighting an inflamed area in the abdominal region. The names of the editors, Maxine A. Papadakis, Michael W. Rabow, Kenneth R. McQuaid, and Associate Editor Monica Gandhi, are listed at the bottom right. The McGraw Hill and LANGE logos are positioned at the bottom.

Book Metadata


  • Full Title: 2025 CURRENT Medical Diagnosis & Treatment
  • Editors: Maxine A. Papadakis, MD; Michael W. Rabow, MD; and Kenneth R. McQuaid, MD
  • Associate Editor: Monica Gandhi, MD, MPH
  • Contributing Authors: A comprehensive list of specialists from various academic institutions, including the University of California, San Francisco
  • Year of Publication: 2025
  • Edition: Sixty-Fourth Edition
  • Total Number of Pages: 1857 pages.


Copyright Summary


This work is published by McGraw Hill and is the sixty-fourth edition of the text. The book is protected under the United States Copyright Act of 1976, and its ISBN is 978-1-2662-6623-2. A standard legal notice accompanies the text, reminding practitioners that medicine is an ever-changing science and that they must verify drug dosages and contraindications against the latest product information.


Preface Analysis


The authors intend for CMDT 2025 to serve as a single-source reference for adult medical practice in both hospital and ambulatory settings. It aims to fill the clinical gap created by the rapid pace of medical advances by providing an annual update that focuses on the practical features of diagnosis and patient management. Since 2020, the editors have also prioritized a formal process to remove biased language and promote equity within medical recommendations.

The primary intended audience includes:

  • Medical students and house officers seeking diagnostic and therapeutic modalities with current citations.
  • Internists, family physicians, and hospitalists requiring a ready reference or refresher text.
  • Nurse practitioners and physician associates who value a quick-reference format for medical diagnosis.
  • Other healthcare professionals, such as pharmacists and dentists.


Chapter List


  • The following chapters are included in the 2025 edition:
  • Disease Prevention & Health Promotion
  • Common Symptoms
  • Preoperative Evaluation & Perioperative Management
  • Geriatric Disorders
  • Palliative Care & Pain Management
  • Dermatologic Disorders
  • Disorders of the Eyes & Lids
  • Otolaryngology Disorders
  • Pulmonary Disorders
  • Coronary Artery Disease, Valvular Disease, & Other Key Topics in Cardiology
  • Heart Failure & Cardiomyopathy
  • Disorders of Cardiac Rhythm
  • Systemic Hypertension
  • Blood Vessel & Lymphatic Disorders
  • Blood Disorders
  • Disorders of Hemostasis, Thrombosis, & Antithrombotic Therapy
  • Gastrointestinal Disorders
  • Liver, Biliary Tract, & Pancreas Disorders
  • Breast Disorders
  • Gynecologic Disorders
  • Obstetrics & Obstetric Disorders
  • Rheumatologic, Immunologic, & Allergic Disorders
  • Electrolyte & Acid-Base Disorders
  • Kidney Disease
  • Urologic Disorders
  • Nervous System Disorders
  • Psychiatric Disorders
  • Endocrine Disorders
  • Diabetes Mellitus & Hypoglycemia
  • Lipid Disorders
  • Nutrition, Nutritional Disorders, & Obesity
  • Common Problems in Infectious Diseases & Antimicrobial Therapy
  • HIV Infection & AIDS
  • Viral & Rickettsial Infections
  • Bacterial & Chlamydial Infections
  • Spirochetal Infections
  • Protozoal & Helminthic Infections
  • Mycotic Infections
  • Disorders Related to Environmental Emergencies
  • Poisoning
  • Cancer
  • Genetic & Genomic Disorders
  • Orthopedic Disorders & Sports Medicine
  • Sexual & Gender Minority Health
  • Substance Use Disorders


Online-Only E-Chapters:


  • e1. Anti-infective Treatment: Antibiotic, Antifungal, and Antiviral Agents
  • e2. Diagnostic Testing & Medical Decision-Making
  • e3. Information Technology in Patient Care
  • e4. Podiatric Disorders
  • e5. Women’s Health Issues
  • e6. Appendix: Therapeutic Drug Monitoring, Laboratory Reference Intervals, & Commonly Used Blood Specimen Collection Tubes


Clinical Value Prop: Why Read This?


For the practicing physician, CMDT 2025 provides an efficient mechanism for staying current with the latest clinical developments. The "Year in Review" section highlights the most significant changes in the past year, such as new USPSTF lung cancer screening guidelines and the approval of lecanemab for early Alzheimer's disease. 


With coverage of over 1,000 diseases, an at-a-glance format for busy clinics, and the inclusion of PubMed identifiers for rapid literature review, it remains a foundational tool for evidence-based internal medicine.








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